PHRF1

Across TCGA patient cohorts, PHRF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,626 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHRF1-associated genes across cancer lineages are PSMD13, RIC8A, and ARFIP2. Each is linked with PHRF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PHRF1-to-partner and partner-to-PHRF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHRF1 versus PSMD13 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHRF1→partner) and Y-score (partner→PHRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSMD13 →	+0.524	+0.348	<.001	.001	3	6
LSCC	RIC8A →	+0.290	+0.154	<.001	<.001	3	5
OV	ARFIP2 →	+0.554	+0.327	<.001	.003	3	4
UCEC	TSSC4 →	+1.093	+0.127	.007	.007	2	5
LSCC	PTDSS2 →	+0.521	+0.240	<.001	<.001	3	4
OV	CERCAM →	-0.999	-0.344	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,626 associations by consensus.

PHRF1 vs PSMD13 — OV

Explore this scatter interactively →