PHOSPHO2

Across TCGA cell cohorts, PHOSPHO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,231 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PHOSPHO2-associated GO terms across cancer lineages are Cytoskeleton-dependent intracellular transport, External encapsulating structure organization, and Protein localization to cytoplasmic stress granule. Each is linked with PHOSPHO2 in more than 12 cancer types. Because this analysis shows association rather than direction, both PHOSPHO2-to-partner and partner-to-PHOSPHO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent intracellular transport grouped by PHOSPHO2-low versus PHOSPHO2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHOSPHO2→partner) and Y-score (partner→PHOSPHO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.064	+0.753	<.001	<.001	3	13
SOFT_TISSUE	External encapsulating structure organization →	-0.129	-0.560	<.001	.002	3	12
URINARY_TRACT	Protein localization to cytoplasmic stress granule →	+0.123	+1.151	.002	<.001	3	11
LUNG_NSCLC_LUSC	mRNA 3'-end processing →	+0.076	+0.646	.001	.004	2	12
BONE	Transport along microtubule →	+0.043	+0.700	<.001	.002	2	12
SOFT_TISSUE	Extracellular matrix organization →	-0.129	-0.560	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,231 associations by consensus.

Cytoskeleton-dependent intracellular transport by PHOSPHO2 expression — LUNG_SCLC

Explore this box plot interactively →