PHKG2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PHKG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PHKG2-associated GO terms across cancer lineages are Promoter clearance during DNA-templated transcription, RNA polymerase II promoter clearance, and Viral transcription. Each is linked with PHKG2 in more than 14 cancer types. Because this analysis shows association rather than direction, both PHKG2-to-partner and partner-to-PHKG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Promoter clearance during DNA-templated transcription grouped by PHKG2-low versus PHKG2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKG2→partner) and Y-score (partner→PHKG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTPromoter clearance during DNA-templated transcription →+0.128+0.795<.001<.001314
URINARY_TRACTRNA polymerase II promoter clearance →+0.128+0.795<.001<.001314
BONEViral transcription →+0.143+0.909<.001<.001314
LIVERLate viral transcription →+0.151+0.812<.001.006215
UPPER_AERODIGESTIVE_TRACTPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.152+0.920<.001<.001314
SOFT_TISSUERegulation of mRNA splicing, via spliceosome →+0.088+0.706.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,162 associations by consensus.

Promoter clearance during DNA-templated transcription by PHKG2 expression — URINARY_TRACT

Box plot of Promoter clearance during DNA-templated transcription in PHKG2-low vs PHKG2-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration