PHKG1

Across TCGA patient cohorts, PHKG1 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHKG1-associated genes across cancer lineages are Adipocytes, Monocytes, and Class-switched memory B-cells. Each is linked with PHKG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHKG1-to-partner and partner-to-PHKG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by PHKG1-low versus PHKG1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKG1→partner) and Y-score (partner→PHKG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Adipocytes →	+0.036	+3.431	.029	.020	3	1
COAD	Monocytes →	+0.028	+4.734	<.001	.045	3	1
UCEC	Class-switched memory B-cells →	-0.047	-2.584	.030	.001	3	1
UCEC	Epithelial cells →	-0.072	-2.211	.009	.010	3	1
UCEC	Macrophages M2 →	+0.008	+2.435	.038	.016	3	1
UCEC	Myocytes →	+0.029	+2.338	.017	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Adipocytes by PHKG1 expression — COAD

Explore this box plot interactively →