PHKG1

Across TCGA cell cohorts, PHKG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,575 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PHKG1-associated GO terms across cancer lineages are Regulation of RNA splicing, Viral transcription, and Regulation of alternative mRNA splicing, via spliceosome. Each is linked with PHKG1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PHKG1-to-partner and partner-to-PHKG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by PHKG1-low versus PHKG1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKG1→partner) and Y-score (partner→PHKG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.097	+0.671	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Viral transcription →	+0.100	+0.423	.004	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.082	+0.519	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.102	+0.657	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.133	-0.599	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.113	+0.653	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,575 associations by consensus.

Regulation of RNA splicing by PHKG1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →