Across TCGA pan-cancer cohorts, PHKBP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PHKBP1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where PHKBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PHKBP1 is over-expressed in tumor.

BRCA and LIHC are the cancer types where PHKBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PHKBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.005	.025	2	view →
LIHC	Male	All	+0.004	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PHKBP1 RNA expression & survival · all PHKBP1 data types