PHKB

Across TCGA cell cohorts, PHKB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,022 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PHKB-associated GO terms across cancer lineages are Late viral transcription, Regulation of Golgi inheritance, and Regulation of locomotion involved in locomotory behavior. Each is linked with PHKB in more than 11 cancer types. Because this analysis shows association rather than direction, both PHKB-to-partner and partner-to-PHKB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late viral transcription grouped by PHKB-low versus PHKB-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKB→partner) and Y-score (partner→PHKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.133	+1.299	.002	<.001	3	12
OVARY	Regulation of Golgi inheritance →	+0.148	+1.020	.001	<.001	3	12
BLOOD_Lymphoma	Regulation of locomotion involved in locomotory behavior →	+0.254	+1.115	<.001	<.001	3	12
BLOOD_Myeloma	Basolateral protein secretion →	+0.191	+1.040	.001	<.001	3	11
LUNG_SCLC	Viral transcription →	+0.108	+0.686	.003	.001	3	11
BONE	Golgi vesicle transport →	+0.054	+0.751	.002	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,022 associations by consensus.

Late viral transcription by PHKB expression — UPPER_AERODIGESTIVE_TRACT

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