PHKA2

Across TCGA patient cohorts, PHKA2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,282 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHKA2-associated genes across cancer lineages are PTBP1, NCAPH, and PLAU. Each is linked with PHKA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHKA2-to-partner and partner-to-PHKA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHKA2 versus PTBP1 in UCEC, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKA2→partner) and Y-score (partner→PHKA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTBP1 →	-0.458	-0.156	<.001	.002	3	3
UCEC	NCAPH →	-0.759	-0.151	<.001	<.001	3	3
LUAD	PLAU →	-1.302	-0.174	<.001	.002	3	3
UCEC	ANP32B →	-0.516	-0.128	<.001	.005	3	3
UCEC	MRPL9 →	-0.568	-0.169	.001	.001	3	3
GBM	HASPIN →	-0.645	-0.175	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,282 associations by consensus.

PHKA2 vs PTBP1 — UCEC

Explore this scatter interactively →