PHKA1P1

Across TCGA pan-cancer cohorts, PHKA1P1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PHKA1P1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher PHKA1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PHKA1P1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

LUSC, UCS, and KIRC are the cancer types where PHKA1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Quartile	III,IV	0.247	0.862	.008	33	view →
UCS	DFS	Tertile	IV	0.936	0.364	.024	24	view →
KIRC	DFS	Tertile	IV	0.180	0.518	.002	20	view →
LUAD	OS	Quartile	All	0.539	0.739	.010	18	view →
DLBC	DFS	Quartile	All	0.512	1.000	.006	16	view →
CHOL	OS	Median	IV	0.208	0.948	.010	12	view →
HNSC	OS	Median	IV	0.799	0.659	.012	11	view →
CESC	DFS	Median	All	0.787	0.855	.017	10	view →
READ	OS	Tertile	II,III,IV	0.783	0.313	.007	10	view →
KIRP	DFS	Median	All	0.882	0.948	.028	7	view →
SKCM	DFS	Quartile	All	0.263	0.133	.004	6	view →
THYM	DFS	Median	III,IV	1.000	0.479	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PHKA1P1–LUSC (DFS)

Open the LUSC breakdown →