PHKA1

Across TCGA patient cohorts, PHKA1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,478 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHKA1-associated genes across cancer lineages are PHKB, LONP2, and FSD1. Each is linked with PHKA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PHKA1-to-partner and partner-to-PHKA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHKA1 versus PHKB in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKA1→partner) and Y-score (partner→PHKA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PHKB →	+0.736	+0.585	<.001	<.001	3	5
BRCA	LONP2 →	+0.715	+0.437	<.001	<.001	3	5
BRCA	FSD1 →	-0.922	-0.417	<.001	.001	3	5
LSCC	ETS1 →	-0.837	-0.345	<.001	<.001	3	5
BRCA	SLC22A5 →	+0.718	+0.382	.001	.001	3	5
LUAD	PHKA1-AS1 →	+0.610	+0.457	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,478 associations by consensus.

PHKA1 vs PHKB — OV

Explore this scatter interactively →