PHKA1

Across TCGA cell cohorts, PHKA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PHKA1-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Positive regulation of translation, and Nuclear-transcribed mRNA catabolic process. Each is linked with PHKA1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PHKA1-to-partner and partner-to-PHKA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by PHKA1-low versus PHKA1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKA1→partner) and Y-score (partner→PHKA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of telomerase RNA localization to Cajal body →	+0.088	+1.332	.004	.005	3	11
LARGE_INTESTINE	Positive regulation of translation →	+0.058	+1.104	<.001	<.001	3	9
LARGE_INTESTINE	Nuclear-transcribed mRNA catabolic process →	+0.038	+0.970	.005	.001	3	9
OVARY	Copper ion export →	-0.195	-1.232	<.001	<.001	3	8
OVARY	Negative regulation of heterochromatin organization →	+0.103	+0.855	<.001	.002	3	8
OVARY	Negative regulation of heterochromatin formation →	+0.103	+0.855	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by PHKA1 expression — STOMACH

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