PHKA1-AS1

Across TCGA pan-cancer cohorts, PHKA1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PHKA1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PHKA1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PHKA1-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and LUSC show a favorable association.

KIRC, CESC, and THYM are the cancer types where PHKA1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.808	0.906	.001	60	view →
CESC	OS	Median	III,IV	0.878	0.641	.009	44	view →
THYM	OS	Median	All	0.642	0.980	.002	41	view →
LUAD	DFS	Median	All	0.580	0.719	.019	27	view →
LUSC	OS	Median	II,III,IV	0.485	0.286	.010	25	view →
SKCM	OS	Quartile	All	0.486	0.297	.001	19	view →
ESCA	OS	Median	III,IV	0.523	0.316	.021	18	view →
BRCA	DFS	Tertile	III,IV	0.915	0.834	.015	15	view →
LGG	DFS	Tertile	All	0.620	0.802	.001	12	view →
UVM	OS	Tertile	II,III,IV	1.000	0.759	.041	6	view →
STAD	DFS	Quartile	IV	0.136	0.490	.011	6	view →
GBM	DFS	Median	All	0.161	0.239	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PHKA1-AS1–KIRC (OS)

Open the KIRC breakdown →