PHGR1

Across TCGA cell cohorts, PHGR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,231 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PHGR1-associated GO terms across cancer lineages are Megakaryocyte differentiation, Secretion by tissue, and Regulation of cytotoxic T cell degranulation. Each is linked with PHGR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PHGR1-to-partner and partner-to-PHGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Megakaryocyte differentiation grouped by PHGR1-low versus PHGR1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHGR1→partner) and Y-score (partner→PHGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Megakaryocyte differentiation →	-0.080	-3.333	<.001	<.001	3	7
STOMACH	Secretion by tissue →	+0.385	+3.813	.001	.003	3	6
STOMACH	Regulation of cytotoxic T cell degranulation →	+1.052	+3.089	<.001	<.001	3	6
STOMACH	Negative regulation of cytotoxic T cell degranulation →	+1.052	+3.089	<.001	<.001	3	6
STOMACH	Golgi to endosome transport →	+0.083	+2.272	.003	.008	3	6
BLOOD_Lymphoma	Collagen fibril organization →	-0.067	-0.169	.004	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,231 associations by consensus.

Megakaryocyte differentiation by PHGR1 expression — LARGE_INTESTINE

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