PHF7

Across TCGA cell cohorts, PHF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,031 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PHF7-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Regulation of sister chromatid segregation, and DNA biosynthetic process. Each is linked with PHF7 in more than 10 cancer types. Because this analysis shows association rather than direction, both PHF7-to-partner and partner-to-PHF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by PHF7-low versus PHF7-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF7→partner) and Y-score (partner→PHF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Microtubule cytoskeleton organization involved in mitosis →	+0.075	+0.710	.001	.008	3	11
BREAST	Regulation of sister chromatid segregation →	+0.086	+0.990	.001	<.001	3	11
STOMACH	DNA biosynthetic process →	+0.061	+1.091	.004	.005	3	11
URINARY_TRACT	DNA synthesis involved in DNA repair →	+0.101	+1.621	<.001	<.001	3	11
STOMACH	Negative regulation of osteoclast proliferation →	+1.212	+1.299	<.001	<.001	3	11
KIDNEY	Regulation of chromosome organization →	+0.063	+0.844	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,031 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by PHF7 expression — OVARY

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