PHF5FP

Across TCGA pan-cancer cohorts, PHF5FP RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PHF5FP’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where PHF5FP RNA is repressed in tumor relative to normal tissue. In most cancer types PHF5FP is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC and KIRP are the cancer types where PHF5FP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PHF5FP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.137	.005	4	view →
KIRP	Female	All	+0.117	.026	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

PHF5FP–LUSC

Open the LUSC breakdown →