Q-omics provides the consensus-scored PHF5CP profile across patient tissues and cancer cell-line models. PHF5CP expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, PHF5CP is differentially expressed in 8, with the highest sampling consensus in THCA. Additionally, PHF5CP RNA expression shows 9,863 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight HNSC, THCA, and GBM as cancer lineages where PHF5CP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PHF5CP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PHF5CP survival associations across molecular data types. PHF5CP RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PHF5CP RNA expression–survival associations across cancer types. High PHF5CP expression shows unfavorable associations in MESO and THCA, but favorable associations in HNSC, OV, CESC and BLCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for PHF5CP RNA expression.
This table summarizes PHF5CP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for PHF5CP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PHF5CP shows lower tumor expression in THCA and higher tumor expression in STAD, KIRC, COAD, HNSC and UCEC. The THCA box plot shows higher PHF5CP RNA expression in normal versus tumor tissue (log2 FC = −0.698, t-test p < 0.001).
This table shows molecular features associated with PHF5CP in patient tissues and cancer cell lines. In patient samples, PHF5CP shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
