PHF3

Across TCGA patient cohorts, PHF3 RNA expression is significantly associated with the RNA expression of many other genes, with 21,467 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PHF3-associated genes across cancer lineages are FOXO3, UBN1, and FBXW2. Each is linked with PHF3 in more than 33 cancer types. Because this analysis shows association rather than direction, both PHF3-to-partner and partner-to-PHF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF3 versus FOXO3 in CHOL, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF3→partner) and Y-score (partner→PHF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	FOXO3 →	+1.443	+1.148	.002	<.001	3	34
SCLC	UBN1 →	+1.425	+1.043	<.001	<.001	3	34
UVM	FBXW2 →	+1.127	+1.476	<.001	<.001	3	34
ACC	YLPM1 →	+1.176	+1.153	<.001	<.001	3	34
DLBC	ATAD2B →	+1.304	+1.463	<.001	<.001	3	34
UVM	KANSL1 →	+1.124	+1.443	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,467 associations by consensus.

PHF3 vs FOXO3 — CHOL

Explore this scatter interactively →