PHF3

Across TCGA patient cohorts, PHF3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,273 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PHF3-associated genes across cancer lineages are F13A1, CFH, and ACVR2B. Each is linked with PHF3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PHF3-to-partner and partner-to-PHF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF3 versus F13A1 in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF3→partner) and Y-score (partner→PHF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	F13A1 →	-1.990	-0.245	<.001	<.001	3	6
GBM	CFH →	-1.114	-0.211	.001	.002	3	6
HNSC	ACVR2B →	+0.593	+0.202	<.001	<.001	3	6
LSCC	CDKAL1 →	+0.737	+0.199	<.001	<.001	3	6
HNSC	TBP →	+0.666	+0.266	.002	<.001	3	6
BRCA	RMND1 →	+0.769	+0.189	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,273 associations by consensus.

PHF3 vs F13A1 — GBM

Explore this scatter interactively →