Across TCGA patient cohorts, PHF2P2 mutation is significantly associated with the RNA expression of many other genes, with 742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHF2P2-associated genes across cancer lineages are OR10K1, NDUFAF2, and DDX10. Each is linked with PHF2P2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHF2P2-to-partner and partner-to-PHF2P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF2P2→partner) and Y-score (partner→PHF2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR10K1 →	+0.125	+5.444	<.001	.002	3	3
UCEC	NDUFAF2 →	+0.535	+3.470	.003	.002	3	2
UCEC	DDX10 →	+0.434	+2.609	.008	.005	3	2
UCEC	NCAPH2 →	+0.439	+3.716	.004	<.001	3	2
UCEC	SCD →	+0.740	+1.960	.007	.009	3	2
SKCM	FTH1P9 →	+0.025	+4.421	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

Exploration

PHF2P2 survival (RNA) · tumor vs normal (RNA) · all PHF2P2 data types