Across TCGA patient cohorts, PHF2P2 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHF2P2-associated genes across cancer lineages are IGFBP2, VHL, and Caspase-7-cleavedD198. Each is linked with PHF2P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF2P2-to-partner and partner-to-PHF2P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF2P2→partner) and Y-score (partner→PHF2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.709	-2.321	.010	.034	3	2
UCEC	VHL →	-1.393	-3.807	<.001	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.716	+2.479	.004	.010	3	2
UCEC	4E-BP1 →	+0.347	+2.906	.002	.001	3	2
UCEC	14-3-3_beta →	-0.111	-2.209	.009	.011	3	1
UCEC	eEF2 →	+0.382	+1.700	.011	.044	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

PHF2P2 survival (RNA) · tumor vs normal (RNA) · all PHF2P2 data types