PHF24

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PHF24 protein abundance is significantly associated with the RNA expression of many other genes, with 6,196 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHF24-associated genes across cancer lineages are SNRPD3, PRODH, and RPS6KA5. Each is linked with PHF24 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF24-to-partner and partner-to-PHF24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF24 versus SNRPD3 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF24→partner) and Y-score (partner→PHF24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSNRPD3 →+0.642+0.975.001.00532
LSCCPRODH →+1.414+1.548.003<.00132
LSCCRPS6KA5 →+0.722+1.426.009<.00132
LSCCPAK5 →+1.570+1.156<.001<.00132
GBMSEC14L5 →+1.520+0.948<.001<.00132
GBMMAST1 →+0.701+0.985<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,196 associations by consensus.

PHF24 vs SNRPD3 — LSCC

Per-sample scatter of PHF24 vs SNRPD3 in LSCC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration