PHF24

Across TCGA cell cohorts, PHF24 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,554 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible PHF24-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with PHF24 in more than 9 cancer types. Because this analysis shows association rather than direction, both PHF24-to-partner and partner-to-PHF24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by PHF24-low versus PHF24-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF24→partner) and Y-score (partner→PHF24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.093	+0.253	<.001	.003	3	10
STOMACH	Negative regulation of myoblast fusion →	+0.126	+0.157	<.001	.004	3	9
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.123	+0.190	<.001	.002	3	9
BONE	Protein insertion into ER membrane →	+0.107	+0.164	.002	.008	2	9
KIDNEY	Regulation of myoblast fusion →	+0.094	+0.194	<.001	.009	3	8
CNS	mRNA catabolic process →	+0.025	+0.106	.003	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,554 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by PHF24 expression — KIDNEY

Explore this box plot interactively →