PHF24

Across TCGA cell cohorts, PHF24 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PHF24-associated genes across cancer lineages are AVP, PIP, and TMEM174. Each is linked with PHF24 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF24-to-partner and partner-to-PHF24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by PHF24-low versus PHF24-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF24→partner) and Y-score (partner→PHF24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+4.794	<.001	<.001	3	1
BLOOD_Lymphoma	PIP →	+0.129	+3.843	<.001	.007	3	1
BLOOD_Lymphoma	TMEM174 →	+0.333	+3.736	<.001	.009	3	1
BLOOD_Lymphoma	RTP1 →	+0.052	+3.954	<.001	.005	3	1
BLOOD_Lymphoma	DEFB124 →	+0.130	+3.927	<.001	.004	3	1
LARGE_INTESTINE	REG1B →	+1.531	+2.933	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

AVP by PHF24 expression — BLOOD_Lymphoma

Explore this box plot interactively →