PHF21B

Across TCGA patient cohorts, PHF21B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,779 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHF21B-associated proteins across cancer lineages are SARM1, HDGFL3, and RBM47. Each is linked with PHF21B in more than 4 cancer types. Because this analysis shows association rather than direction, both PHF21B-to-partner and partner-to-PHF21B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF21B versus SARM1 in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF21B→partner) and Y-score (partner→PHF21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SARM1 →	+0.430	+0.641	<.001	.001	3	5
UCEC	HDGFL3 →	+0.608	+0.703	<.001	<.001	3	5
GBM	RBM47 →	-0.530	-0.730	<.001	<.001	3	4
GBM	UAP1 →	-0.438	-0.669	<.001	<.001	3	4
GBM	ADSS2 →	-0.269	-0.862	.005	.001	3	4
UCEC	CROCC →	+0.479	+0.856	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,779 associations by consensus.

PHF21B vs SARM1 — BRCA

Explore this scatter interactively →