PHF21B

Across TCGA patient cohorts, PHF21B protein abundance is significantly associated with the protein abundance of many other proteins, with 530 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHF21B-associated proteins across cancer lineages are RELL1, RIPK2, and TBC1D22B_S154. Each is linked with PHF21B in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF21B-to-partner and partner-to-PHF21B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF21B versus RELL1 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF21B→partner) and Y-score (partner→PHF21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RELL1 →	+0.538	+1.431	.004	.004	2	1
BRCA	RIPK2 →	-0.827	-2.322	.004	.008	2	1
BRCA	TBC1D22B_S154 →	-0.737	-2.050	.007	.003	2	1
BRCA	TMEM131 →	-0.745	-2.199	<.001	.002	2	1
BRCA	TOMM40 →	-1.236	-2.254	<.001	.001	2	1
BRCA	TPPP →	+1.266	+2.366	<.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

PHF21B vs RELL1 — BRCA

Explore this scatter interactively →