PHF20L1

Across TCGA patient cohorts, PHF20L1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,706 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHF20L1-associated genes across cancer lineages are VRK1, ATAD2, and MTBP. Each is linked with PHF20L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PHF20L1-to-partner and partner-to-PHF20L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF20L1 versus VRK1 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF20L1→partner) and Y-score (partner→PHF20L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.696	+0.179	<.001	<.001	3	6
UCEC	ATAD2 →	+0.915	+0.205	<.001	.002	3	6
UCEC	MTBP →	+0.719	+0.257	<.001	<.001	3	6
LSCC	STMN1 →	+1.010	+0.266	<.001	<.001	3	5
BRCA	NUDCD1 →	+0.654	+0.365	<.001	<.001	3	5
UCEC	DSCC1 →	+1.099	+0.209	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,706 associations by consensus.

PHF20L1 vs VRK1 — LSCC

Explore this scatter interactively →