PHF20L1

Across TCGA cell cohorts, PHF20L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,764 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PHF20L1-associated GO terms across cancer lineages are Negative regulation of proteasomal protein catabolic process, RNA destabilization, and RNA export from nucleus. Each is linked with PHF20L1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PHF20L1-to-partner and partner-to-PHF20L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of proteasomal protein catabolic process grouped by PHF20L1-low versus PHF20L1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF20L1→partner) and Y-score (partner→PHF20L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of proteasomal protein catabolic process →	+0.080	+0.932	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	RNA destabilization →	+0.058	+0.899	.003	.005	3	14
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.138	+1.103	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.078	+1.013	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA metabolic process →	+0.064	+1.043	.001	<.001	3	13
STOMACH	Stress granule assembly →	+0.121	+0.771	.002	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,764 associations by consensus.

Negative regulation of proteasomal protein catabolic process by PHF20L1 expression — OVARY

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