PHF20L1

Across TCGA cell cohorts, PHF20L1 mutation is significantly associated with the RNA expression of many other genes, with 1,044 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PHF20L1-associated genes across cancer lineages are OR10W1, NUP88, and C1QBP. Each is linked with PHF20L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF20L1-to-partner and partner-to-PHF20L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by PHF20L1-low versus PHF20L1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF20L1→partner) and Y-score (partner→PHF20L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10W1 →	+0.008	+4.196	<.001	.006	3	2
LARGE_INTESTINE	NUP88 →	+0.646	+2.404	<.001	.004	3	2
LARGE_INTESTINE	C1QBP →	+0.866	+3.936	<.001	<.001	3	2
LARGE_INTESTINE	RSL24D1 →	+0.505	+2.743	.002	.001	3	2
LARGE_INTESTINE	C18orf21 →	+0.682	+2.523	<.001	.003	3	2
LARGE_INTESTINE	ARRB2 →	+0.725	+3.169	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,044 associations by consensus.

OR10W1 by PHF20L1 expression — BREAST

Explore this box plot interactively →