PHF20

Across TCGA patient cohorts, PHF20 protein abundance is significantly associated with the RNA expression of many other genes, with 3,060 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHF20-associated genes across cancer lineages are USP1, FAM72A, and SCML2. Each is linked with PHF20 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHF20-to-partner and partner-to-PHF20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF20 versus USP1 in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF20→partner) and Y-score (partner→PHF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	USP1 →	+0.703	+0.587	.001	<.001	3	3
UCEC	FAM72A →	+0.515	+0.266	.007	<.001	3	3
UCEC	SCML2 →	+0.814	+0.278	.005	.006	3	3
LSCC	RBM39 →	+0.451	+0.457	<.001	<.001	3	3
UCEC	CEBPB-AS1 →	+0.426	+0.253	.006	.004	3	3
UCEC	ZNF670 →	+0.677	+0.308	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,060 associations by consensus.

PHF20 vs USP1 — GBM

Explore this scatter interactively →