PHF20

Across TCGA cell cohorts, PHF20 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,249 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PHF20-associated GO terms across cancer lineages are Regulation of centriole-centriole cohesion, Regulation of cell division, and Metaphase chromosome alignment. Each is linked with PHF20 in more than 11 cancer types. Because this analysis shows association rather than direction, both PHF20-to-partner and partner-to-PHF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole-centriole cohesion grouped by PHF20-low versus PHF20-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF20→partner) and Y-score (partner→PHF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of centriole-centriole cohesion →	+0.152	+0.783	.001	.001	3	12
SOFT_TISSUE	Regulation of cell division →	+0.092	+0.755	<.001	<.001	3	10
SOFT_TISSUE	Metaphase chromosome alignment →	+0.107	+0.727	<.001	<.001	3	10
SOFT_TISSUE	Immunoglobulin heavy chain V-D-J recombination →	+0.199	+0.900	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of chromosome condensation →	+0.215	+0.900	<.001	<.001	3	10
SOFT_TISSUE	Protein localization to condensed chromosome →	+0.144	+0.802	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,249 associations by consensus.

Regulation of centriole-centriole cohesion by PHF20 expression — OVARY

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