PHF19

Across TCGA patient cohorts, PHF19 protein abundance is significantly associated with the RNA expression of many other genes, with 8,229 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHF19-associated genes across cancer lineages are HHLA2, PPP5C, and IGFBP5. Each is linked with PHF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF19-to-partner and partner-to-PHF19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF19 versus HHLA2 in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF19→partner) and Y-score (partner→PHF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HHLA2 →	+0.172	+0.618	.009	.004	3	1
GBM	PPP5C →	+0.856	+0.750	.003	.002	3	1
GBM	IGFBP5 →	-1.311	-0.658	.006	.003	3	1
GBM	P4HA1 →	-1.093	-0.755	.004	.002	3	1
GBM	ZNF576 →	+0.629	+0.746	.001	.002	3	1
GBM	SPIRE1 →	+1.004	+0.744	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,229 associations by consensus.

PHF19 vs HHLA2 — GBM

Explore this scatter interactively →