PHF19

Across TCGA patient cohorts, PHF19 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,405 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHF19-associated proteins across cancer lineages are RTF1_S60, SEMA4D_S798, and SRSF7_S183. Each is linked with PHF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF19-to-partner and partner-to-PHF19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF19 versus RTF1_S60 in GBM, with a Pearson correlation of 0.90.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF19→partner) and Y-score (partner→PHF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RTF1_S60 →	+2.633	+0.570	<.001	.002	3	1
GBM	SEMA4D_S798 →	+0.716	+0.620	<.001	.001	3	1
GBM	SRSF7_S183 →	+1.313	+0.566	.002	.002	3	1
GBM	SRSF7_S213 →	+1.505	+0.559	<.001	.003	3	1
GBM	SRSF7_S215 →	+1.505	+0.559	<.001	.003	3	1
GBM	SRSF7_S217 →	+2.603	+0.619	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,405 associations by consensus.

PHF19 vs RTF1_S60 — GBM

Explore this scatter interactively →