PHF19

Across TCGA patient cohorts, PHF19 mutation is significantly associated with the RNA expression of many other genes, with 3,817 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHF19-associated genes across cancer lineages are VTRNA2-2P, RNU6-1089P, and LINC02210-CRHR1. Each is linked with PHF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF19-to-partner and partner-to-PHF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VTRNA2-2P grouped by PHF19-low versus PHF19-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF19→partner) and Y-score (partner→PHF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	VTRNA2-2P →	+0.534	+3.953	<.001	.005	3	2
SKCM	RNU6-1089P →	+0.412	+5.356	<.001	<.001	3	2
SKCM	LINC02210-CRHR1 →	+0.145	+3.838	<.001	.006	3	2
UCEC	IGHD2-2 →	+0.879	+1.872	.007	<.001	3	2
UCEC	SNORD90 →	+0.205	+1.814	.002	.007	3	2
UCEC	RNA5SP408 →	+0.241	+2.450	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,817 associations by consensus.

VTRNA2-2P by PHF19 expression — SKCM

Explore this box plot interactively →