PHF14

Across TCGA cell cohorts, PHF14 mutation is significantly associated with the mutation status of many other genes, with 3,993 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PHF14-associated genes across cancer lineages are RBM33, ATG9A, and PTPRA. Each is linked with PHF14 in more than 4 cancer types. Because this analysis shows association rather than direction, both PHF14-to-partner and partner-to-PHF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBM33 grouped by PHF14-low versus PHF14-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF14→partner) and Y-score (partner→PHF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RBM33 →	+4.437	+5.000	.007	.007	1	5
BONE	ATG9A →	+5.437	+5.437	.003	.003	1	5
BLOOD_Leukemia	PTPRA →	+3.870	+4.050	.002	.002	1	5
BLOOD_Leukemia	ZNF496 →	+3.063	+3.498	.006	.006	1	5
BLOOD_Leukemia	FMN1 →	+3.285	+3.662	.004	.004	1	5
BLOOD_Lymphoma	RSF1 →	+5.247	+4.429	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,993 associations by consensus.

RBM33 by PHF14 expression — BONE

Explore this box plot interactively →