PHF13

Across TCGA patient cohorts, PHF13 mutation is significantly associated with the RNA expression of many other genes, with 4,351 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHF13-associated genes across cancer lineages are TRAJ38, RNU6-1216P, and TEX50. Each is linked with PHF13 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHF13-to-partner and partner-to-PHF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ38 grouped by PHF13-low versus PHF13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF13→partner) and Y-score (partner→PHF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ38 →	+0.333	+2.048	.001	.002	3	3
SKCM	RNU6-1216P →	+0.348	+4.118	<.001	.004	3	2
COAD	TEX50 →	+0.165	+5.824	<.001	.001	3	2
UCEC	RNA5SP491 →	+0.252	+1.677	.007	.006	3	2
UCEC	RNU6-668P →	+0.193	+2.449	<.001	.007	3	2
UCEC	TRAJ57 →	+0.372	+2.038	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,351 associations by consensus.

TRAJ38 by PHF13 expression — UCEC

Explore this box plot interactively →