PHF11

Across TCGA patient cohorts, PHF11 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,321 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PHF11-associated proteins across cancer lineages are PHF11_S17, TRIM21, and DDX58. Each is linked with PHF11 in more than 6 cancer types. Because this analysis shows association rather than direction, both PHF11-to-partner and partner-to-PHF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF11 versus PHF11_S17 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF11→partner) and Y-score (partner→PHF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PHF11_S17 →	+0.557	+0.472	<.001	<.001	3	7
HNSC	TRIM21 →	+0.549	+0.518	<.001	<.001	3	6
LSCC	DDX58 →	+0.611	+0.476	<.001	<.001	3	6
HNSC	DDX60 →	+0.511	+0.433	.001	<.001	3	6
OV	SHFL →	+0.364	+0.459	<.001	.001	3	6
COAD	ABCD1 →	+0.473	+0.432	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,321 associations by consensus.

PHF11 vs PHF11_S17 — HNSC

Explore this scatter interactively →