PHF11

Across TCGA patient cohorts, PHF11 protein abundance is significantly associated with the RNA expression of many other genes, with 11,668 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHF11-associated genes across cancer lineages are APOL3, PIK3CG, and AKNA. Each is linked with PHF11 in more than 5 cancer types. Because this analysis shows association rather than direction, both PHF11-to-partner and partner-to-PHF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF11 versus APOL3 in HNSC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF11→partner) and Y-score (partner→PHF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	APOL3 →	+1.112	+0.423	<.001	<.001	3	6
HNSC	PIK3CG →	+1.173	+0.593	<.001	<.001	3	6
HNSC	AKNA →	+1.032	+0.612	<.001	<.001	3	6
HNSC	CCR2 →	+1.379	+0.559	<.001	<.001	3	6
HNSC	IL16 →	+0.766	+0.506	<.001	<.001	3	6
HNSC	TRBJ2-7 →	+2.070	+0.507	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,668 associations by consensus.

PHF11 vs APOL3 — HNSC

Explore this scatter interactively →