PHF11

Across TCGA cell cohorts, PHF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,448 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PHF11-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous peptide antigen, Antigen processing and presentation, and Antigen processing and presentation of endogenous peptide antigen via MHC class I. Each is linked with PHF11 in more than 13 cancer types. Because this analysis shows association rather than direction, both PHF11-to-partner and partner-to-PHF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of endogenous peptide antigen grouped by PHF11-low versus PHF11-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF11→partner) and Y-score (partner→PHF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Antigen processing and presentation of endogenous peptide antigen →	+0.250	+1.552	<.001	<.001	3	14
BONE	Antigen processing and presentation →	+0.179	+3.185	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.246	+1.164	<.001	<.001	3	12
BONE	Antigen processing and presentation of peptide antigen →	+0.168	+2.867	<.001	<.001	3	12
BLOOD_Lymphoma	Pattern recognition receptor signaling pathway →	+0.065	+1.157	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of CD8-positive, alpha-beta T cell proliferation →	+0.278	+2.073	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,448 associations by consensus.

Antigen processing and presentation of endogenous peptide antigen by PHF11 expression — CNS

Explore this box plot interactively →