PHF10

Across TCGA cell cohorts, PHF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,783 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PHF10-associated GO terms across cancer lineages are Regulation of chromosome organization, Termination of RNA polymerase II transcription, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with PHF10 in more than 14 cancer types. Because this analysis shows association rather than direction, both PHF10-to-partner and partner-to-PHF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome organization grouped by PHF10-low versus PHF10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF10→partner) and Y-score (partner→PHF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of chromosome organization →	+0.078	+0.496	.009	.002	3	15
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.156	+1.252	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of metaphase/anaphase transition of cell cycle →	+0.111	+1.074	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of mitotic metaphase/anaphase transition →	+0.118	+1.124	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of sister chromatid segregation →	+0.114	+1.074	<.001	<.001	3	14
LUNG_SCLC	Negative regulation of ubiquitin protein ligase activity →	+0.218	+1.180	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,783 associations by consensus.

Regulation of chromosome organization by PHF10 expression — BONE

Explore this box plot interactively →