PHETA2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PHETA2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHETA2-associated genes across cancer lineages are Preadipocytes, CD8+ Tem, and MEP. Each is linked with PHETA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHETA2-to-partner and partner-to-PHETA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by PHETA2-low versus PHETA2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHETA2→partner) and Y-score (partner→PHETA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPreadipocytes →+0.033+4.754.042.00331
UCECCD8+ Tem →+0.001+4.744.010.04031
UCECMEP →+0.042+2.180.003.03611
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Preadipocytes by PHETA2 expression — COAD

Box plot of Preadipocytes in PHETA2-low vs PHETA2-high samples in COAD.

Explore this box plot interactively →

Exploration