Across TCGA patient cohorts, PHETA1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,437 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHETA1-associated genes across cancer lineages are SYTL2, COA6, and ARHGAP18. Each is linked with PHETA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHETA1-to-partner and partner-to-PHETA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHETA1→partner) and Y-score (partner→PHETA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SYTL2 →	+1.783	+0.493	.008	.001	3	3
COAD	COA6 →	-0.776	-0.497	.003	.005	3	3
OV	ARHGAP18 →	+0.679	+0.661	.004	<.001	3	3
COAD	MIF4GD →	-0.928	-0.497	.003	.005	3	2
COAD	ATP5MC2 →	-0.813	-0.513	<.001	.007	3	2
COAD	KIF13B →	+0.992	+0.518	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,437 associations by consensus.

Exploration

PHETA1 survival (RNA) · tumor vs normal (RNA) · all PHETA1 data types