Across TCGA cell cohorts, PHETA1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PHETA1-associated genes across cancer lineages are AADACL4, C20orf85, and TECTB. Each is linked with PHETA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHETA1-to-partner and partner-to-PHETA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHETA1→partner) and Y-score (partner→PHETA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AADACL4 →	+0.026	+4.922	<.001	.009	3	1
OVARY	C20orf85 →	+0.449	+5.196	<.001	.005	3	1
BLOOD_Lymphoma	TECTB →	+0.063	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	NEUROG1 →	+0.006	+5.643	<.001	.002	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.005	+2.777	.003	.004	3	1
LARGE_INTESTINE	TFDP3 →	+0.019	+2.518	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

PHETA1 survival (RNA) · tumor vs normal (RNA) · all PHETA1 data types