PHBP20

Across TCGA pan-cancer cohorts, PHBP20 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PHBP20 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PHBP20 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PHBP20 expression acts as an unfavorable survival marker, although some lineages such as ACC and LIHC show a favorable association.

KIRC, UVM, and UCS are the cancer types where PHBP20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.541	0.704	<.001	54	view →
UVM	OS	Tertile	All	0.629	0.935	.012	35	view →
UCS	DFS	Tertile	IV	0.239	0.936	.024	24	view →
STAD	DFS	Quartile	II,III,IV	0.442	0.757	.021	22	view →
HNSC	OS	Quartile	All	0.691	0.805	.014	18	view →
READ	OS	Tertile	IV	0.439	0.878	.004	16	view →
OV	DFS	Quartile	II,III,IV	0.119	0.199	.019	14	view →
ACC	DFS	Quartile	IV	0.641	0.108	.006	12	view →
KICH	DFS	Tertile	All	0.711	1.000	.026	9	view →
MESO	DFS	Median	II,III,IV	0.296	0.566	.023	9	view →
DLBC	DFS	Tertile	IV	0.120	0.827	.025	9	view →
THCA	DFS	Quartile	IV	0.780	1.000	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PHBP20–KIRC (DFS)

Open the KIRC breakdown →