PHBP13

Across TCGA pan-cancer cohorts, PHBP13 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PHBP13 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PHBP13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PHBP13 expression acts as an unfavorable survival marker, although some lineages such as PAAD and THYM show a favorable association.

UCEC, KIRP, and LIHC are the cancer types where PHBP13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.852	0.918	<.001	116	view →
KIRP	OS	Quartile	II,III,IV	0.540	0.874	.001	53	view →
LIHC	OS	Tertile	III,IV	0.314	0.661	<.001	48	view →
ACC	OS	Quartile	All	0.633	0.991	.005	45	view →
PAAD	OS	Median	All	0.585	0.268	<.001	39	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.733	.005	23	view →
LGG	DFS	Tertile	All	0.318	0.487	.013	21	view →
LUAD	DFS	Quartile	II,III,IV	0.301	0.550	.003	20	view →
BRCA	DFS	Median	IV	0.324	0.699	.006	20	view →
STAD	DFS	Quartile	All	0.467	0.625	.022	12	view →
UVM	OS	Tertile	III,IV	0.444	0.804	.025	7	view →
ESCA	OS	Tertile	IV	0.238	0.597	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PHBP13–UCEC (DFS)

Open the UCEC breakdown →