PHBP10

Across TCGA pan-cancer cohorts, PHBP10 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PHBP10 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PHBP10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PHBP10 expression acts as an unfavorable survival marker, although some lineages such as PAAD and SKCM show a favorable association.

LUAD, PAAD, and CHOL are the cancer types where PHBP10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	III,IV	0.377	0.736	<.001	98	view →
PAAD	OS	Tertile	II,III,IV	0.688	0.317	.002	60	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
MESO	OS	Tertile	III,IV	0.238	0.610	<.001	18	view →
LGG	OS	Tertile	All	0.723	0.858	.004	18	view →
OV	OS	Quartile	II,III,IV	0.636	0.747	.014	16	view →
READ	OS	Quartile	IV	0.468	0.958	.002	10	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
UVM	DFS	Tertile	III,IV	0.184	0.708	.018	9	view →
SKCM	DFS	Median	IV	0.560	0.156	.031	9	view →
KIRP	DFS	Tertile	II,III,IV	1.000	0.454	.040	8	view →
THYM	DFS	Tertile	All	0.950	0.690	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PHBP10–LUAD (OS)

Open the LUAD breakdown →