PHB2P1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, PHB2P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PHB2P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PHB2P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PHB2P1 is over-expressed in tumor.

COAD and HNSC are the cancer types where PHB2P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PHB2P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllAll+0.118<.0015view →
HNSCMaleAll+0.011.0411view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

PHB2P1–COAD

Tumor-vs-normal expression box plot for PHB2P1 RNA in COAD.

Open the COAD breakdown →

Exploration