Across TCGA patient cohorts, PHB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,590 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHB2-associated proteins across cancer lineages are NIP7, NOP2, and NOP16. Each is linked with PHB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PHB2-to-partner and partner-to-PHB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHB2→partner) and Y-score (partner→PHB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NIP7 →	+0.486	+0.614	<.001	<.001	3	8
BRCA	NOP2 →	+0.598	+0.553	.001	.007	3	8
OV	NOP16 →	+0.462	+0.637	.003	.002	3	7
GBM	PA2G4 →	+0.252	+0.201	.003	.005	3	7
OV	PHB →	+0.409	+0.667	<.001	<.001	3	7
OV	INTS13 →	+0.424	+0.959	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,590 associations by consensus.

Exploration

PHB2 survival (RNA) · tumor vs normal (RNA) · all PHB2 data types