Across TCGA patient cohorts, PHB2 mutation is significantly associated with the RNA expression of many other genes, with 1,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHB2-associated genes across cancer lineages are LINC00692, CYCSP20, and OR9L1P. Each is linked with PHB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHB2-to-partner and partner-to-PHB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHB2→partner) and Y-score (partner→PHB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	LINC00692 →	+0.041	+5.266	.003	.006	3	2
LUAD	CYCSP20 →	+0.254	+5.343	<.001	.006	3	2
UCEC	OR9L1P →	+0.081	+2.622	<.001	.007	3	2
UCEC	OR4B2P →	+0.104	+3.484	<.001	<.001	3	2
LUSC	RNA5SP426 →	+0.318	+7.924	<.001	.008	3	2
UCEC	ECM1P1 →	+0.128	+2.161	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,277 associations by consensus.

Exploration

PHB2 survival (RNA) · tumor vs normal (RNA) · all PHB2 data types