PHAX

Across TCGA cell cohorts, PHAX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,012 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PHAX-associated GO terms across cancer lineages are Positive regulation of cell cycle, Regulation of nuclear division, and Negative regulation of mitotic metaphase/anaphase transition. Each is linked with PHAX in more than 13 cancer types. Because this analysis shows association rather than direction, both PHAX-to-partner and partner-to-PHAX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle grouped by PHAX-low versus PHAX-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHAX→partner) and Y-score (partner→PHAX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of cell cycle →	+0.055	+0.797	.004	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of nuclear division →	+0.114	+0.994	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic metaphase/anaphase transition →	+0.164	+0.749	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome segregation →	+0.103	+0.775	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.065	+0.809	<.001	<.001	3	13
BREAST	Centriole replication →	+0.110	+0.860	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,012 associations by consensus.

Positive regulation of cell cycle by PHAX expression — STOMACH

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