PGRMC2

Across TCGA patient cohorts, PGRMC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,797 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PGRMC2-associated proteins across cancer lineages are CASP6, TRAF3IP3, and RPL26. Each is linked with PGRMC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PGRMC2-to-partner and partner-to-PGRMC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGRMC2 versus CASP6 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGRMC2→partner) and Y-score (partner→PGRMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CASP6 →	+0.590	+0.541	<.001	<.001	3	4
BRCA	TRAF3IP3 →	-0.443	-0.443	<.001	<.001	3	4
LUAD	RPL26 →	-0.520	-0.323	.001	.003	3	4
BRCA	PLCG2 →	-0.478	-0.481	.001	.001	3	4
BRCA	PMVK →	+0.446	+0.606	<.001	<.001	3	4
CCRCC	MEF2C_S396 →	-0.409	-0.492	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,797 associations by consensus.

PGRMC2 vs CASP6 — OV

Explore this scatter interactively →